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Home » By Dietary Need » High Protein

High Protein Chicken Enchiladas

Published: May 20, 2025 by Matilda · This post may contain affiliate links · Leave a Comment

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Welcome to my kitchen, friends! Today I'm sharing one of my absolute favorite dinner recipes that has become a staple in my weekly meal rotation. These High Protein Chicken Enchiladas are the perfect balance of comfort food and nutrition - packed with lean protein, wrapped in tortillas, and smothered in delicious enchilada sauce and melty cheese.

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Close-up of melted cheese on enchiladas with fresh cilantro leaves this recipe

I'm not saying this is addictive, but I've made it three times this week. There's something about the combination of seasoned chicken, tangy Greek yogurt, and that perfect cheese pull when you take your first bite that keeps me coming back for more. Plus, with over 30 grams of protein per serving, these enchiladas are perfect for anyone looking to increase their protein intake without sacrificing flavor.

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Whether you're meal prepping for the week ahead or feeding a hungry family, this recipe delivers big on flavor while keeping preparation simple. The best part? You can have these enchiladas on the table in under 45 minutes, making them perfect for busy weeknights when you need a satisfying dinner solution.

What You'll Love About This Recipe

  • Protein-Packed - With Greek yogurt, refried beans, and plenty of chicken, each enchilada delivers serious protein to keep you satisfied.
  • Meal-Prep Friendly - These enchiladas reheat beautifully, making them perfect for batch cooking and enjoying throughout the week.
  • Customizable - Easily adjust the spice level, protein source, or toppings to suit your preferences and what you have on hand.

Recipe Ingredients

These High Protein Chicken Enchiladas come together with simple ingredients you might already have in your kitchen. Here's what you'll need:

  • Refried beans
  • Greek yogurt
  • Taco seasoning
  • Shredded cooked chicken
  • Mexican cheese blend
  • Red enchilada sauce
  • Flour tortillas
  • Optional garnishes like cilantro, avocado, or sour cream
See recipe card below for a full list of ingredients and measurements.

Our Recommended Equipment

How to Make High Protein Chicken Enchiladas

This recipe comes together quickly with minimal fuss. For the complete recipe with exact measurements, scroll down to the printable recipe card. Here's the step-by-step process:

  1. Preheat and prepare - Get your oven ready at 375°F and prepare your baking dish with non-stick spray.
  2. Mix the filling - Combine Greek yogurt, refried beans, and taco seasoning, then fold in shredded chicken and some cheese.

Bowl with Greek yogurt, taco seasoning, and refried beans being mixed for enchilada filling
Bowl filled with shredded cooked chicken, shredded cheese, and creamy refried bean mixture for enchilada filling
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  1. Fill tortillas - Add about ⅓ cup of filling to each tortilla and roll tightly.
  2. Arrange - Place the rolled enchiladas seam-side down in your baking dish.

Corn tortillas being filled with chicken, cheese, and bean mixture on a flat surface before rolling
Rolled chicken enchiladas lined in a baking dish and covered in red enchilada sauce before baking

  1. Top with sauce and cheese - Pour enchilada sauce over the tortillas and sprinkle with remaining cheese.
  2. Bake - Cook for 15-20 minutes until the cheese is melted and bubbly.
  3. Serve - Garnish as desired and enjoy your protein-packed meal!

Enchiladas layered with shredded cheese and enchilada sauce in a white casserole dish
Hot and bubbly enchiladas fresh from the oven, topped with melted cheese and fresh cilantro
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Pro Tips

This recipe is my go-to for a quick dinner fix, and I've picked up some tricks along the way! For the best High Protein Chicken Enchiladas, try warming your tortillas for about 10-15 seconds in the microwave before filling them. This makes them more pliable and less likely to tear when rolling. Also, don't overstuff your enchiladas—it might be tempting, but keeping to about ⅓ cup of filling ensures they'll roll properly and cook evenly.

Storage and Reheating

  • Refrigeration - Store leftover enchiladas in an airtight container for up to 4 days. The flavors actually develop nicely overnight, making them even more delicious the next day! 
  • Freezing - These enchiladas freeze beautifully! Freeze individual portions or the entire casserole (pre-baked) for up to 3 months.
  • Reheating - For best results, reheat refrigerated enchiladas in a 350°F oven for 15-20 minutes until heated through. Microwave individual portions for 2-3 minutes, covered with a damp paper towel to prevent drying out. See my guide on reheating leftovers without losing flavor.

Additions & Substitutions

Additions:

  • Add a layer of black beans or corn between the enchiladas for extra fiber and texture
  • Include diced bell peppers or jalapeños in the filling for added vegetables and flavor
  • Top with fresh avocado, pico de gallo, or a dollop of Greek yogurt after baking
  • Sprinkle with sliced green onions or black olives for extra color and flavor

Substitutions:

  • Swap the chicken for ground turkey or lean ground beef if preferred
  • Use low-carb tortillas to reduce the carbohydrate content while maintaining the protein
  • Replace the red enchilada sauce with green enchilada sauce for a different flavor profile
  • Substitute the refried beans with black bean puree for a different texture and flavor

FAQs About These Easy High Protein Chicken Enchiladas

Can I use frozen chicken for these enchiladas?
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Yes! Thaw frozen chicken completely before shredding and incorporating into the filling. For convenience, you can cook frozen chicken breasts in an Instant Pot or slow cooker, then shred for this recipe.

How can I make these enchiladas spicier?

Add diced jalapeños or a few dashes of hot sauce to the filling mixture. You can also use "hot" enchilada sauce instead of mild, or sprinkle red pepper flakes on top before baking.

Are there any vegetarian alternatives to these enchiladas?

Absolutely! Replace the chicken with a mixture of black beans, quinoa, and sautéed vegetables for a high-protein vegetarian version that's equally satisfying and nutritious.

What Can I Serve with These High Protein Chicken Enchiladas?

These High Protein Chicken Enchiladas are hearty enough to stand alone as a complete meal, but if you're feeding a crowd or want to round out your dinner, consider serving them with a simple side salad, cilantro lime rice, or roasted vegetables. The enchiladas bring plenty of protein to the table, so lighter sides with fresh vegetables make for a perfectly balanced meal.

If you try this recipe, I'd be thrilled to hear how it turned out for you! Drop a comment below or tag me in your social media posts. Your feedback helps me create more recipes you'll love!

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Baked chicken enchiladas with cheese and cilantro alongside recipe title text overlay

Full Recipe:

Hot and bubbly enchiladas fresh from the oven, topped with melted cheese and fresh cilantro

High Protein Chicken Enchiladas

These enchiladas are packed with protein and flavor, perfect for a healthy and hearty meal.
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Course: Main Course
Cuisine: Mexican
Keyword: Chicken, Enchiladas, High Protein
Prep Time: 15 minutes minutes
Cook Time: 20 minutes minutes
Total Time: 35 minutes minutes
Servings: 4 servings
Calories: 479kcal

Equipment

  • 9x13 inch baking dish

Ingredients

Filling

  • ½ cup refried beans
  • ¾ cup Greek yogurt
  • 1 tablespoon taco seasoning
  • 3 cups shredded cooked chicken
  • 1.5 cups shredded Mexican cheese divided

Assembly

  • 10 oz can red enchilada sauce
  • 8 flour tortillas (8-inch, high fiber recommended)

Instructions

  • Preheat your oven to 375°F (190°C). Lightly spray a 9x13-inch baking dish with nonstick cooking spray and set it aside.
  • In a medium bowl, combine the Greek yogurt, refried beans, and taco seasoning. Mix well. Stir in the shredded chicken and ½ cup of the shredded Mexican cheese.
  • Lay out your tortillas. Scoop about ⅓ cup (or 80g) of the chicken mixture evenly into the center of each tortilla.
  • Roll each tortilla tightly and place them seam-side down in a single row in your prepared baking dish.
  • Pour the entire can of red enchilada sauce over the rolled tortillas. Sprinkle the remaining 1 cup of shredded Mexican cheese on top.
  • Bake for 15-20 minutes, or until the cheese is melted and bubbly.
  • Garnish with fresh cilantro, if desired, and enjoy!

Notes

Use rotisserie chicken, grilled chicken, or leftover baked chicken for the filling. You can add jalapeños for extra spice.

Nutrition

Calories: 479kcal | Carbohydrates: 43.6g | Protein: 38.2g | Fat: 16.9g | Saturated Fat: 7.5g | Cholesterol: 81.2mg | Fiber: 23.3g | Sugar: 3.4g

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